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CyFlow™ CD10 APC-Cy7

CyFlow™ CD10 APC-Cy7
Antigen: CD10
Alternative Name: CALLA, gp100, NEP
Clone: MEM-78
Application: Flow cytometry
Format/Fluorochrome: APC-Cy7
Laser: Red
Target Species: Human
Field of Interest: Immunophenotyping
Species of Origin: Mouse
Regulatory Status: RUO
Clonality: monoclonal
Emission Maximum: 780 nm
Excitation Maximum: 650 nm, 750 nm
Isotype: IgG1
Order number: BT633988

For Research Use Only
Not for use in diagnostic or therapeutic procedures.

Quantity 100 tests Volume 0.4 ml Immunogen NALM-6 human pre-B cell line Specifity... more
CyFlow™ CD10 APC-Cy7
Quantity100 tests
Volume0.4 ml
ImmunogenNALM-6 human pre-B cell line
SpecifityThe mouse monoclonal antibody MEM-78 recognizes CD10 antigen, a 100 kDa type II integral membrane protein.
Background InformationCD10 (neutral endopeptidase - NEP, common acute lymphocytic leukemia antigen - CALLA, membrane metallo-endopeptidase - MME, enkefalinase) is a 100 kDa cell surface zinc metalloprotease cleaving peptide bonds on the N-terminus of hydrophobic amino acids and inactivating multiple physiologically active peptides. CD10 is expressed on various normal cell types, including lymphoid precursor cells, germinal center B lymhocytes, and some epithelial cells, and its expression level serves as a marker for diagnostics of many carcinomas. CD10 is also a differentiation antigen for early B-lymphoid progenitors in the B-cell differentiation pathway and has a key role in regulation of growth, differentiation and signal transduction of many cellular systems.
UsageThe reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 4·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.
Storage BufferThe reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.1% (w/v) sodium azide.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.

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